Dosing and administration

Scroll or click the links to jump to any section below:
Did you know?

Cimzia maintenance dosing regimen is preceded by a loading dose across all indications.1

Click here to visit emc for the full indication details (SmPC)



Dosing and administration across all indications1

dosing chart
Zoom Icon

Reduced dose in comparison to the initial maintenance dose of 200 mg every 2 weeks may be considered in patients with severe, active axSpA who are in sustained remission after at least 1 year of treatment.1,2,a

Reduced dose
Zoom Icon

Adapted from Cimzia SmPC and Landewé R, et al. Ann Rheum Dis. 2020

Patients received CIMZIA® 200 mg every 2 weeks after a loading dose of CIMZIA® 400 mg at weeks 0, 2 and 4. At week 48, patients in sustained remission (Ankylosing Spondylitis Disease Activity Score (ASDAS) <1.3 at weeks 32 or 36, and 48) were randomised to CIMZIA® 200 mg every 2 weeks (full maintenance dose), CIMZIA® 200 mg every 4 weeks (reduced maintenance dose) or placebo (withdrawal) for an additional 48 weeks.2

Treatment should be guided according to a predefined treatment target.2

After the starting dose, the recommended maintenance dose of Cimzia® for adult patients with axial spondyloarthritis is 200 mg Q2W or 400 mg Q4W. After at least 1 year of treatment with Cimzia®, in patients with sustained remission, a reduced maintenance dose of 200 mg Q4W may be considered.



1. Cimzia® Summary of Product Characteristics. [Accessed April 2021].

2. Landewé R, et al. Ann Rheum Dis. 2020;79(7):920–928.

Because we're in this together...

Report adverse events

Adverse events should be reported. Reporting forms and information can be found at and

Adverse events should also be reported to UCB Pharma Ltd Email: and

Feature requests

Help us to grow our resource the way you want it to grow.

Get in touch now

Date of preparation: December 2022